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DTSTART;TZID=Europe/Berlin:20250402T160000
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UID:4309-1743609600-1743613200@lasers4.eu
SUMMARY:Laserlab-Europe Talk: Boosting multiphoton 3D printing for biomedical engineering: small features\, high impact\, 2 April 2025
DESCRIPTION:Speaker: Irina Alexandra Paun (INFLPR) \n\n\n\n\nThe biomedical engineering sector is one of the most rapidly growing industrial areas\, bringing together engineering\, medicine and biology\, to develop novel technologies for medical treatment. Modern biomedical engineering advanced the concept of “reverse engineering”\, which means building micro- and nano-structures with functional biomimicry by extracting design parameters from biological systems\, such as from cell types and shapes\, and from the complex 3D architectures of extracellular matrix microenvironments. Cells seeded on these 3D micro/nano-structures attach\, interconnect\, proliferate\, and finally form masses of cells organized in 3D architectures closely resembling the natural tissue. These micro/nano-structures are currently used not only for fundamental mechanistic studies on the development\, regeneration\, and repair of damaged human tissues\, but also for diagnostics\, disease modeling\, drug delivery\, and personalized medicine. \nIn this talk\, I will present our recent results on the fusion between reverse engineering and laser processing\, within the scope of current challenges in medical treatments. Specifically\, I will show how we “boosted” a conventional 3D printing technique\, known as Laser Direct Writing via Two-Photon Polymerization (LDW via TPP)\, for biomedical engineering. LDW via TPP has been extensively used for fabricating structures with complex 3D architectures\, for biomedical use. It is known that LDW via TPP offers low operational costs\, rapid processing time\, high spatial resolution\, and full reproducibility of the obtained structures\, mandatory for systematic in vitro studies. In our work\, we targeted the development of innovative\, synergistic combinations of 3D micro/nano-structures fabricated by LDW via TPP and specific structure characteristics such as composition\, morphology\, and surface chemistry. This approach allowed us to obtain better control over attachment\, growth\, and\, in some cases\, differentiation of various cell types\, e.g. osteoblasts\, fibroblasts\, and glial cells. We further improved the effectiveness of the laser-printed structures by volumetric integration of electrically and magnetically responsive biomaterials into the “backbone” of the structures. The electrically or magnetically “active” 3D micro/nano-structures allowed us to accelerate certain processes involved in tissue regeneration by externally applied electric or magnetic stimuli. \nWe expect this approach to emerge in advanced biomedical applications such as tissue engineering\, wound dressings\, and advanced drug delivery systems\, with the final goal of refining patient-oriented treatments. \n\n\n			\n			\n				\n				\n				\n				\n			\n				\n				\n				\n				\n				\n				\n				Watch the Talk
URL:https://lasers4.eu/event/laserlab-europe-talk-boosting-multiphoton-3d-printing-for-biomedical-engineering-small-features-high-impact-2-april-2025/
CATEGORIES:Webinars
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DTSTART;TZID=Europe/Berlin:20250423T160000
DTEND;TZID=Europe/Berlin:20250423T170000
DTSTAMP:20260422T222125
CREATED:20250319T092737Z
LAST-MODIFIED:20250718T065046Z
UID:4460-1745424000-1745427600@lasers4.eu
SUMMARY:Laserlab-Europe Talk: Optical modification of graphene for applications\, 23 April 2025
DESCRIPTION:Speaker: Mika Pettersson (Laserlab-NSC) \nGraphene and other 2D materials have many excellent properties but seldom they can be used as such in advanced applications. One option is to chemically modify and functionalize 2D materials. However\, many applications require spatially selective functionalization and patterning. Laser-based methods offer many advantages in this regard. A common optical material modification technique is laser ablation. However\, for graphene\, more interesting condition is just below the ablation threshold\, where non-linear excitation of material takes place. Under these conditions\, graphene reacts with adsorbed oxygen and water present in ambient air\, leading to oxidative functionalization without breaking the carbon lattice integrity [1]. Interestingly\, optically induced local functionalization of graphene leads to many opportunities for development of applications via processes such as: modification of electronic properties [1]\, locally selective immobilization of proteins [2\,3]\, area-selective atomic or molecular layer deposition [4\,5]\, modification of optical properties [6]\, tuning of the response of sensors [7]\, or affecting molecular self-assembly [8]. The methods can be applied for development of sensors\, (opto)electronic devices\, flexible and transparent electronics\, bioelectronics\, and so on. \nIn this talk\, I will introduce controlled oxidative functionalization of graphene by femtosecond laser excitation and show several examples of how this method can be used to facilitate development of functional devices. \nReferences[1] J. Aumanen et al.\, Nanoscale\, 7\, 2851-2855 (2015).[2] E. D. Sitsanidis et al. Nanoscale Adv. 3\, 2065 – 2074 (2021).[3] A. Lampinen et al. RSC Appl. Interfaces\, 1\, 1305 (2024).[4] K. K. Mentel et al. Adv. Mater. Interfaces 9\, 2201110 (2022).[5] A\, V. Emelianov et al. https://doi.org/10.26434/chemrxiv-2024-81qv0\, ChemRxiv[6] V.-M-. Hiltunen et al. J. Phys. Chem. C\, 124\, 8371 – 8377 (2020).[7] A. Lampinen et al. Phys. Chem. Chem. Phys. 25\, 10778 – 10784 (2023).[8] J. Schirmer et al. Phys. Chem. Chem. Phys. 25\, 8725 – 8733 (2023). \n\n\n			\n				Watch the Talk
URL:https://lasers4.eu/event/laserlab-europe-talk-optical-modification-of-graphene-for-applications/
CATEGORIES:Webinars
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